Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.67 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.52 |
| ▸ | ITGAL | P20701 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2028311 | 0.85 | SLC6A2 (0.68) | SLC6A4SLC6A2SLC6A3PDE7ASMN1; SMN2 | |
| SCHEMBL9132817 | 0.84 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3PDE7ASMN1; SMN2 | |
| SCHEMBL3077375 | 0.82 | SIRT1 (0.77) | SLC6A4SLC6A2SLC6A3SIRT1MAPT | |
| SCHEMBL31272173 | 0.82 | PDE7A (0.78) | SLC6A4SLC6A2SLC6A3PDE7ASMN1; SMN2 | |
| SCHEMBL875772 | 0.82 | PDE7A (0.78) | SLC6A4SLC6A2SLC6A3PDE7ASMN1; SMN2 | |
| SCHEMBL10766788 | 0.81 | CTSD (0.65) | SMN1; SMN2MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL115478 | 0.81 | CTSD (0.65) | SMN1; SMN2MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL1340717 | 0.80 | SLC6A2 (0.70) | SLC6A4SLC6A2SLC6A3PDE7ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10550781 | 0.79 | CTSD (0.62) | SMN1; SMN2MAPTKDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL8025084 | 0.79 | CTSD (0.62) | SMN1; SMN2MAPTKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1037681-C | Tetrazole derivatives and pharmaceutical | NIPPON SHINYAKU CO LTD (JP) | 1998-03-11 | — | — | CN | disclosed |
| US-5399703-A | Antiallergens | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0536400-A1 | TETRAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-14 | — | — | EP | disclosed |
| CN-1063687-A | Terazole derivatives and medicine | NIPPON SHINYAKU CO LTD (JP) | 1992-08-19 | — | — | CN | disclosed |