Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9131337 | 0.85 | GPBAR1 (0.53) | GPBAR1CYSLTR1PDE10ACYSLTR2FFAR1 | |
| SCHEMBL9132216 | 0.79 | CACNA1H (0.53) | MAPK14 | |
| SCHEMBL9131506 | 0.79 | GPBAR1 (0.49) | GPBAR1CYSLTR1PDE10ACYSLTR2 | |
| SCHEMBL9129427 | 0.79 | PLK1 (0.61) | MAPK14 | |
| SCHEMBL9130582 | 0.78 | CACNA1H (0.54) | MAPK14 | |
| SCHEMBL9135886 | 0.76 | ALDH1A1 (0.43) | GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL9132696 | 0.76 | CACNA1H (0.52) | MAPK14 | |
| SCHEMBL3534448 | 0.76 | GPBAR1 (0.74) | GPBAR1CYSLTR1PDE10ACYSLTR2FFAR1 | |
| SCHEMBL9130515 | 0.76 | LMNA (0.58) | MAPK14 | |
| SCHEMBL10663836 | 0.75 | CYSLTR1 (0.56) | GPBAR1CYSLTR1PDE10ACYSLTR2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399703-A | Antiallergens | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0536400-A1 | TETRAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-14 | — | — | EP | disclosed |