Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 5/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129427 | 0.89 | PLK1 (0.61) | CACNA1HCACNA1BMAPK14PLK1RAB9A | |
| SCHEMBL9132216 | 0.88 | CACNA1H (0.53) | CACNA1HCACNA1BMAPK14PLK1RAB9A | |
| SCHEMBL9130795 | 0.88 | CACNA1H (0.50) | CACNA1HCACNA1BMAPK14PLK1RAB9A | |
| SCHEMBL9132696 | 0.86 | CACNA1H (0.52) | CACNA1HCACNA1BMAPK14PLK1RAB9A | |
| SCHEMBL9132468 | 0.85 | CACNA1H (0.52) | CACNA1HCACNA1BMAPK14PLK1RAB9A | |
| SCHEMBL9130724 | 0.83 | PLK1 (0.46) | CACNA1HCACNA1BPLK1CYP3A4BCHE | |
| SCHEMBL9130515 | 0.80 | LMNA (0.58) | CACNA1HCACNA1BMAPK14RAB9AMEN1 | |
| SCHEMBL9130762 | 0.78 | GPBAR1 (0.54) | MAPK14 | |
| SCHEMBL9132805 | 0.75 | PLK1 (0.59) | CACNA1HCACNA1BPLK1RAB9AMEN1 | |
| SCHEMBL9713320 | 0.73 | PLK1 (0.64) | CACNA1HCACNA1BPLK1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399703-A | Antiallergens | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0536400-A1 | TETRAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-14 | — | — | EP | disclosed |