Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 5/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9132468 | 0.96 | CACNA1H (0.52) | CACNA1HCACNA1BPLK1MEN1RAB9A | |
| SCHEMBL9129427 | 0.89 | PLK1 (0.61) | CACNA1HCACNA1BPLK1MEN1RAB9A | |
| SCHEMBL9130515 | 0.88 | LMNA (0.58) | CACNA1HCACNA1BMEN1RAB9AKMT2A | |
| SCHEMBL9130582 | 0.88 | CACNA1H (0.54) | CACNA1HCACNA1BPLK1MEN1RAB9A | |
| SCHEMBL9132216 | 0.86 | CACNA1H (0.53) | CACNA1HCACNA1BPLK1MEN1RAB9A | |
| SCHEMBL9134929 | 0.85 | PLK1 (0.47) | PLK1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL9131666 | 0.84 | PLK1 (0.46) | PLK1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL9128760 | 0.83 | PLK1 (0.46) | PLK1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL9132696 | 0.82 | CACNA1H (0.52) | CACNA1HCACNA1BPLK1MEN1RAB9A | |
| SCHEMBL9131526 | 0.81 | L3MBTL1 (0.50) | PLK1MEN1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399703-A | Antiallergens | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0536400-A1 | TETRAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-14 | — | — | EP | disclosed |