SCHEMBL9130824

SCHEMBL9130824

CC=CCc1cccc(Oc2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
KDM4E B2RXH2 4/20 0.48
HTT P42858 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
EPOR P19235 2/20 0.47
MAOB P27338 1/20 0.47
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
HPGD P15428 1/20 0.44
FFAR1 O14842 2/20 0.43
FFAR4 Q5NUL3 1/20 0.43
ALOX5 P09917 1/20 0.43
ALOX5AP P20292 1/20 0.43
PTGS1 P23219 1/20 0.43
PTGS2 P35354 1/20 0.43
PTGES O14684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10446475 0.85 ALDH1A1 (0.50) ALDH1A1KDM4EHTTTDP1SMN1; SMN2
SCHEMBL10446472 0.85 ALDH1A1 (0.50) ALDH1A1KDM4EHTTTDP1SMN1; SMN2
SCHEMBL28977325 0.84 LTA4H (0.52) MAOBTSHRFFAR1
SCHEMBL14382193 0.83 MAOB (0.58) MAOBFFAR1ALOX5
SCHEMBL4268581 0.83 MAOB (0.58) MAOBFFAR1ALOX5
SCHEMBL10446473 0.83 FFAR1 (0.46) ALDH1A1KDM4EHTTTDP1SMN1; SMN2
SCHEMBL4268579 0.83 MAOB (0.58) MAOBFFAR1ALOX5
SCHEMBL5311815 0.80 KDM4E (0.51) ALDH1A1KDM4EHTTTDP1SMN1; SMN2
SCHEMBL28886740 0.79 TP53 (0.53) ALDH1A1KDM4ESMN1; SMN2TSHR
SCHEMBL27691613 0.79 FFAR1 (0.55) ALDH1A1KDM4ESMN1; SMN2EPORFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5466838-A Catalytic reaction of olefin with oxygen in the presence of aldehyde SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-11-14 US disclosed
EP-0540009-B1 Process for producing epoxides SUMITOMO CHEMICAL CO (JP) 1995-08-30 EP disclosed
US-5367087-A Process for producing epoxide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-22 US disclosed
EP-0540009-A1 Process for producing epoxides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-05 EP disclosed