Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 2/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29515039 | 0.75 | KDM4E (0.36) | LMNASMN1; SMN2HTT | |
| SCHEMBL8335822 | 0.75 | KDM4E (0.36) | LMNASMN1; SMN2HTT | |
| SCHEMBL14114311 | 0.74 | SMN1; SMN2 (0.33) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL29935680 | 0.74 | SMN1; SMN2 (0.33) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL16058987 | 0.71 | SLC6A2 (0.44) | LMNASMN1; SMN2SLC6A2SLC6A4P2RX4 | |
| SCHEMBL30534544 | 0.71 | LMNA (0.32) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL28896942 | 0.70 | MAPT (0.40) | — | |
| SCHEMBL28728701 | 0.69 | LMNA (0.30) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL19699832 | 0.69 | P2RX4 (0.35) | LMNACRHBPCRHR2SMN1; SMN2HTT | |
| SCHEMBL19337001 | 0.69 | KDM4E (0.35) | LMNACRHBPCRHR2SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685584-A | N- (2, 3-dihydro-1, 4-benzoxazin-4-yl) -3-isopropyl-7- (2, 3, 5-trifluorophenyl) benzothiophene-2-carboxamide derivatives and similar compounds for the treatment of heartworm infections | 礼蓝动物保健有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-1037179-C | 1,4-benzoxazino derivatives | SS PHARMACEUTICAL CO (JP) | 1998-01-28 | — | — | CN | disclosed |
| US-5440036-A | For cardiovascular and respiratory system disorders | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| CN-1095064-A | 1, the 4-benzo-oxazine derivative | SS PHARMACEUTICAL CO (JP) | 1994-11-16 | — | — | CN | disclosed |
| EP-0602458-A1 | 1,4-Benzoxazine derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |