Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | SELL | P14151 | 1/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HK2 | P52789 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660344 | 0.98 | IAPP (0.46) | IAPPPRKCISELLSELPESR1 | |
| SCHEMBL5201499 | 0.83 | TYR (0.49) | IAPPPRKCI | |
| SCHEMBL5202172 | 0.82 | ERCC1 (0.41) | IAPPPRKCI | |
| SCHEMBL1426061 | 0.81 | IAPP (0.67) | IAPP | |
| SCHEMBL31013617 | 0.81 | IAPP (0.67) | IAPP | |
| SCHEMBL9025960 | 0.79 | PRKCI (0.42) | PRKCI | |
| SCHEMBL22982305 | 0.79 | SELL (0.44) | SELLSELPESR1ADORA3NPY1R | |
| SCHEMBL31618870 | 0.79 | SELL (0.44) | SELLSELPESR1ADORA3NPY1R | |
| SCHEMBL26046412 | 0.79 | IAPP (0.70) | IAPPPRKCI | |
| SCHEMBL28194562 | 0.79 | PRKCI (0.38) | IAPPPRKCIESR1ADORA3NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442017-A | Addition polymerization in vessel with interior wall coating comprised of condesation product of aromatic amine, aromatic alcohol and acetone plus polymeric material and colloidal silica | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-08-15 | — | — | US | disclosed |