SCHEMBL1426061

SCHEMBL1426061

CC(=O)Cc1cccc(O)c1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IAPP P10997 5/20 0.67
AKR1B1 P15121 1/20 0.47
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
THRB P10828 1/20 0.45
DBH P09172 1/20 0.45
ADAMTS4 O75173 1/20 0.44
ALDH1A1 P00352 1/20 0.44
EGFR P00533 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
LMNA P02545 1/20 0.44
FYN P06241 1/20 0.44
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
MMP8 P22894 1/20 0.44
CA6 P23280 1/20 0.44
CDK2 P24941 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31013617 1.00 IAPP (0.67) IAPPAKR1B1GABRA1GABRB2THRB
SCHEMBL30176200 0.83 AKR1B1 (0.68) IAPPAKR1B1THRBCA2LMNA
SCHEMBL266802 0.83 AKR1B1 (0.68) IAPPAKR1B1THRBCA2LMNA
SCHEMBL660344 0.83 IAPP (0.46) IAPP
SCHEMBL28717700 0.83 IAPP (0.56) IAPPAKR1B1GABRA1GABRB2DBH
SCHEMBL2545614 0.82 IAPP (0.50) IAPPAKR1B1GABRA1GABRB2THRB
SCHEMBL5991730 0.82 ALDH1A1 (0.50) IAPPGABRA1GABRB2ALDH1A1EGFR
SCHEMBL29829095 0.81 AKR1B1 (0.72) IAPPAKR1B1THRBDBHADAMTS4
SCHEMBL8791 0.81 AKR1B1 (0.72) IAPPAKR1B1THRBDBHADAMTS4
SCHEMBL9130849 0.81 IAPP (0.44) IAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117214316-A Method for controlling mass of detumescence and analgesia composition 广西壮族自治区花红药业集团股份公司 2023-12-12 CN claimed
US-20200205541-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND L'OREAL (FR) 2020-07-02 US claimed
US-20130298933-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND L'OREAL (FR) 2013-11-14 US claimed
US-20100300472-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND L'OREAL S.A. (FR) 2010-12-02 US claimed
EP-4740962-A1 PHARMACEUTICAL COMPOSITION, FORMULATION CONTAINING PHARMACEUTICAL COMPOSITION, KIT CONTAINING PHARMACEUTICAL COMPOSITION, PREPARATION METHOD FOR PHARMACEUTICAL COMPOSITION, AND USE OF PHARMACEUTICAL COMPOSITION Shanghai WD Pharmaceutical Co., Ltd (CN) 2026-05-13 EP disclosed
US-20250281390-A1 OSMOTIC PUMP TABLET, PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI WD PHARMACEUTICAL CO., LTD (CN) 2025-09-11 US disclosed
WO-2025007958-A1 PHARMACEUTICAL COMPOSITION, FORMULATION CONTAINING PHARMACEUTICAL COMPOSITION, KIT CONTAINING PHARMACEUTICAL COMPOSITION, PREPARATION METHOD FOR PHARMACEUTICAL COMPOSITION, AND USE OF PHARMACEUTICAL COMPOSITION 上海汉都医药科技有限公司 2025-01-09 WO disclosed
CN-119258225-A Pharmaceutical composition, preparation containing pharmaceutical composition, kit and preparation method and application of pharmaceutical composition 上海汉都医药科技有限公司 2025-01-07 CN disclosed
US-20240269443-A1 ORAL RETENTION DEVICE AND OSMOTIC PUMP TABLET, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SHANGHAI WD PHARMACEUTICAL CO LTD (CN) 2024-08-15 US disclosed
CN-118185788-A Pseudomonas oleovorax and application thereof 青岛蔚蓝赛德生物科技有限公司 2024-06-14 CN disclosed
US-11911513-B2 Controlled-release system of active pharmaceutical ingredient and preparation method therefor SHANGHAI WD PHARMACEUTICAL CO., LTD (CN) 2024-02-27 US disclosed
CN-117214316-A Method for controlling mass of detumescence and analgesia composition 广西壮族自治区花红药业集团股份公司 2023-12-12 CN disclosed
US-20120192888-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS L 'Oréal S.A., (FR) 2012-08-02 US disclosed
EP-1670450-B8 PHARMACEUTICAL COMPOSITIONS AND METHOD OF USING LEVODOPA AND CARBIDOPA CENTOCOR ORTHO BIOTECH INC (US) 2011-03-23 EP disclosed
US-20100300472-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND L'OREAL S.A. (FR) 2010-12-02 US disclosed
US-20100028280-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS L'OREAL S.A. (FR) 2010-02-04 US disclosed
EP-1670450-A4 PHARMACEUTICAL COMPOSITIONS AND METHOD OF USING LEVODOPA AND CARBIDOPA TRANSFORM PHARMACEUTICALS INC (US) 2008-08-27 EP disclosed
EP-1670450-A2 PHARMACEUTICAL COMPOSITIONS AND METHOD OF USING LEVODOPA AND CARBIDOPA Transform Pharmaceuticals, Inc. (US) 2006-06-21 EP disclosed
WO-2005023185-A2 PHARMACEUTICAL COMPOSITIONS AND METHOD OF USING LEVODOPA AND CARBIDOPA TRANSFORM PHARMACEUTICALS, INC. (US) 2005-03-17 WO disclosed
EP-0350069-A2 Method for oxidizing unsaturated aromatic compounds NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1990-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120192888-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS KRT18, KRTCAP2, TUBB4A IAPP 2481/4885AKR1B1 613/4885GABRA1 4655/4885
US-20200205541-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND KRT18, TUBB4A, TUBB4B IAPP 4122/4885AKR1B1 180/4885GABRA1 4755/4885
US-20100028280-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS KRT18, KRTCAP2, TUBB4A IAPP 2481/4885AKR1B1 613/4885GABRA1 4655/4885
US-20100300472-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND KRT18, TUBB4A, TUBB4B IAPP 4122/4885AKR1B1 180/4885GABRA1 4755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.