Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 8/20 | 0.48 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130860 | 0.89 | HTR7 (0.62) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL9132091 | 0.81 | HTR7 (0.52) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL9132049 | 0.80 | HTR7 (0.50) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL9131075 | 0.77 | HTR7 (0.45) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL9131038 | 0.71 | HTR7 (0.44) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL9132098 | 0.70 | HTR7 (0.67) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL9134162 | 0.69 | HTR7 (0.42) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL9132055 | 0.69 | HTR7 (0.65) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL9131871 | 0.68 | DRD2 (0.43) | HTR7DRD2HTR1AHTR2AHTR6 | |
| SCHEMBL9131062 | 0.67 | DRD2 (0.41) | HTR7DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453437-A | 1,3-disubstituted pyrrolidines | BAYER AKTIENGESELLSCHAFT (DE) | 1995-09-26 | — | — | US | disclosed |