Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.68 |
| ▸ | CA2 | P00918 | 15/20 | 0.67 |
| ▸ | CA1 | P00915 | 14/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052055 | 0.85 | CA2 (0.71) | GAACA2CA1CA5AKMT2A | |
| SCHEMBL11358253 | 0.83 | CA2 (0.68) | GAACA2CA1CA5AKMT2A | |
| SCHEMBL10725236 | 0.82 | LMNA (0.50) | GAACA2CA1CA5A | |
| SCHEMBL28616093 | 0.82 | CA2 (0.67) | GAACA2CA1CA5AKMT2A | |
| SCHEMBL28102126 | 0.81 | CA2 (0.70) | GAACA2CA1CA5AKMT2A | |
| SCHEMBL6990778 | 0.80 | KMT2A (0.74) | CA2CA1KMT2ACA4CA12 | |
| SCHEMBL31604259 | 0.79 | CA1 (0.62) | CA2CA1CA4CA12CA9 | |
| SCHEMBL28884752 | 0.78 | CA2 (0.67) | GAACA2CA1CA5AKMT2A | |
| SCHEMBL13945440 | 0.76 | GAA (0.78) | GAACA2CA1KMT2ACA4 | |
| Hydrochloric Acid SCHEMBL11027004 | 0.76 | CA2 (0.65) | GAACA2CA1CA5AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411967-A | Antiinflammatory, immunosuppressant, antitumor | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-05-02 | — | — | US | claimed |
| US-5411967-A | Antiinflammatory, immunosuppressant, antitumor | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-05-02 | — | — | US | disclosed |