Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493082 | 0.82 | MEN1 (0.64) | LSSALDH1A1HTTLMNAMEN1 | |
| SCHEMBL9130927 | 0.79 | LSS (0.90) | LSSALDH1A1HTTLMNAMEN1 | |
| SCHEMBL9483898 | 0.79 | MEN1 (0.56) | LSSALDH1A1HTTLMNAMEN1 | |
| SCHEMBL7502501 | 0.78 | LTA4H (0.50) | ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL9131391 | 0.78 | LSS (0.65) | LSSALDH1A1HTTLMNAMEN1 | |
| SCHEMBL6731066 | 0.78 | SIGMAR1 (0.43) | ALDH1A1LMNAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL9483947 | 0.78 | MEN1 (0.59) | ALDH1A1HTTLMNAMEN1KMT2A | |
| SCHEMBL9129519 | 0.78 | LSS (0.76) | LSSALDH1A1HTTLMNAMEN1 | |
| SCHEMBL9172903 | 0.77 | LSS (0.64) | LSS | |
| SCHEMBL10589292 | 0.77 | ALDH1A1 (0.86) | ALDH1A1MEN1KMT2ASMN1; SMN2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564499-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-13 | — | — | EP | disclosed |