Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520861 | 0.81 | TDP1 (0.52) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL8520862 | 0.81 | TDP1 (0.52) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| Benzene SCHEMBL11235066 | 0.73 | CYP1A2 (0.56) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| Benzene SCHEMBL7716364 | 0.73 | CYP1A2 (0.56) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL2740846 | 0.72 | SIGMAR1 (0.56) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL7650795 | 0.71 | CYP1A2 (0.58) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL2291745 | 0.71 | CYP1A2 (0.58) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL49212 | 0.71 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL9305261 | 0.69 | TDP1 (0.48) | ALDH1A1HPGDHSD17B10CYP3A4TSHR | |
| SCHEMBL28496032 | 0.69 | CYP1A2 (0.56) | ALDH1A1HPGDHSD17B10CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424309-A | Hypotensive agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |