SCHEMBL8520862

SCHEMBL8520862

c1ccc(NN=Nc2cccc3ccccc23)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.52
TSHR P16473 2/20 0.52
CYP1A1 P04798 1/20 0.52
CYP1B1 Q16678 1/20 0.52
MEN1 O00255 6/20 0.44
KMT2A Q03164 6/20 0.44
RAB9A P51151 5/20 0.44
NPC1 O15118 4/20 0.44
CASP3 P42574 2/20 0.44
SENP8 Q96LD8 2/20 0.44
SENP7 Q9BQF6 2/20 0.44
SENP6 Q9GZR1 2/20 0.44
ALDH1A1 P00352 5/20 0.44
HPGD P15428 4/20 0.44
CYP3A4 P08684 3/20 0.44
ALOX15 P16050 2/20 0.44
HSD17B10 Q99714 2/20 0.44
TP53 P04637 1/20 0.44
CDC25B P30305 1/20 0.44
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8520861 1.00 TDP1 (0.52) TDP1TSHRCYP1A1CYP1B1MEN1
SCHEMBL4908899 0.81 SIGMAR1 (0.50) TDP1TSHRMEN1KMT2ARAB9A
SCHEMBL22062012 0.81 SIGMAR1 (0.50) TDP1TSHRMEN1KMT2ARAB9A
SCHEMBL9130960 0.81 ALDH1A1 (0.47) TDP1TSHRCYP1A1CYP1B1MEN1
Benzene SCHEMBL7716364 0.80 CYP1A2 (0.56) TDP1TSHRMEN1KMT2ANPC1
Benzene SCHEMBL11235066 0.80 CYP1A2 (0.56) TDP1TSHRMEN1KMT2ANPC1
SCHEMBL3324095 0.79 CYP1A1 (0.39) TDP1TSHRCYP1A1CYP1B1MEN1
SCHEMBL2291745 0.77 CYP1A2 (0.58) TDP1TSHRMEN1KMT2ANPC1
SCHEMBL7650795 0.77 CYP1A2 (0.58) TDP1TSHRMEN1KMT2ANPC1
SCHEMBL28496032 0.75 CYP1A2 (0.56) TDP1TSHRCYP1B1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103597040-B High electrical insulating properties azo system black pigment, manufacture method, coloured composition, colorize method and dyed articles class DAINICHISEIKA COLOR & CHEMICALS MFG. CO.,LTD. (JP) 2016-01-27 CN claimed
CN-103597040-A Highly electrically insulating azo-based black pigment, production method, colored composition, coloring method, and colored articles DAINICHISEIKA COLOR CHEM 2014-02-19 CN claimed
EP-0629249-B1 PROCESS FOR THE DYEING OF CELLULOSE-CONTAINING FIBRE MATERIALS WITH REACTIVE DYES CIBA GEIGY AG (CH) 1997-01-08 EP claimed
US-5525124-A IN PRESENCE OF REDUCED CONCENTRATION OF A MINERAL ACID SALT CIBA-GEIGY CORPORATION (US) 1996-06-11 US claimed
EP-0629249-A1 PROCESS FOR THE DYEING OF CELLULOSE-CONTAINING FIBRE MATERIALS WITH REACTIVE DYES. CIBA GEIGY AG (CH) 1994-12-21 EP claimed
EP-0298041-B1 Reactive dyes, their preparation and their use CIBA GEIGY AG (CH) 1994-06-08 EP claimed
WO-1993018224-A1 PROCESS FOR THE DYEING OF CELLULOSE-CONTAINING FIBRE MATERIALS WITH REACTIVE DYES CIBA-GEIGY AG (CH) 1993-09-16 WO claimed
EP-0470930-A1 Reactive dyes, their preparation and use CIBA-GEIGY AG (CH) 1992-02-12 EP claimed
US-4900813-A Fiber-reactive azo dyes having a 4,6-diaminopyridine coupling component CIBA-GEIGY CORPORATION (US) 1990-02-13 US claimed
CN-103597040-B High electrical insulating properties azo system black pigment, manufacture method, coloured composition, colorize method and dyed articles class DAINICHISEIKA COLOR & CHEMICALS MFG. CO.,LTD. (JP) 2016-01-27 CN disclosed
CN-103597040-A Highly electrically insulating azo-based black pigment, production method, colored composition, coloring method, and colored articles DAINICHISEIKA COLOR CHEM 2014-02-19 CN disclosed
EP-0631008-B1 Process for the washing of printings or dyeings on cellulose containing textile materials CIBA GEIGY AG (CH) 1999-08-18 EP disclosed
EP-0629249-B1 PROCESS FOR THE DYEING OF CELLULOSE-CONTAINING FIBRE MATERIALS WITH REACTIVE DYES CIBA GEIGY AG (CH) 1997-01-08 EP disclosed
US-5525124-A IN PRESENCE OF REDUCED CONCENTRATION OF A MINERAL ACID SALT CIBA-GEIGY CORPORATION (US) 1996-06-11 US disclosed
WO-1993018224-A1 PROCESS FOR THE DYEING OF CELLULOSE-CONTAINING FIBRE MATERIALS WITH REACTIVE DYES CIBA-GEIGY AG (CH) 1993-09-16 WO disclosed
EP-0470930-A1 Reactive dyes, their preparation and use CIBA-GEIGY AG (CH) 1992-02-12 EP disclosed
US-4975530-A 4,6-diaminopyrimidine or the like intermediates for the preparation of fiber-reactive dyes CIBA-GEIGY CORPORATION (US) 1990-12-04 US disclosed
US-4900813-A Fiber-reactive azo dyes having a 4,6-diaminopyridine coupling component CIBA-GEIGY CORPORATION (US) 1990-02-13 US disclosed
EP-0298041-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1989-01-04 EP disclosed
US-3932379-A Water-soluble maroon and rubine sulphodiphenylazophenyl- or naphthylazoaniline dyes for polyamide fibers Althouse Tertre en abrege "Atsa" societe anonyme (BE) 1976-01-13 US disclosed