Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11829843 | 0.80 | SUMO2 (0.53) | MAPTTDP1L3MBTL1KMT2AHPGD | |
| SCHEMBL10521527 | 0.80 | CYP1A2 (0.57) | KDM4ELMNAMAPTOPRK1HTT | |
| SCHEMBL4639218 | 0.80 | CYP1A2 (0.57) | KDM4ELMNAMAPTOPRK1HTT | |
| SCHEMBL10593663 | 0.77 | CYP2D6 (0.51) | MAPTTDP1KMT2AHPGDCYP1A2 | |
| SCHEMBL21686429 | 0.76 | PHLPP2 (0.61) | KDM4ELMNAMAPTOPRK1HTT | |
| SCHEMBL284105 | 0.76 | L3MBTL1 (1.00) | KDM4ELMNAMAPTOPRK1HTT | |
| SCHEMBL31621738 | 0.76 | L3MBTL1 (1.00) | KDM4ELMNAMAPTOPRK1HTT | |
| SCHEMBL284106 | 0.76 | L3MBTL1 (1.00) | KDM4ELMNAMAPTOPRK1HTT | |
| SCHEMBL11407326 | 0.74 | LMNA (0.62) | KDM4ELMNAMAPTOPRK1HTT | |
| SCHEMBL11407323 | 0.74 | LMNA (0.62) | KDM4ELMNAMAPTOPRK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5421897-A | Applying liquid composition to surface contaminated with lead, solidifying into matrix which sequesters lead, removing matrix | GRAWE JOHN (US) | 1995-06-06 | — | — | US | disclosed |