Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 5/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130186 | 0.92 | HTR1B (0.60) | HTR1BHTR1AHDAC3BRD4HDAC4 | |
| SCHEMBL9132886 | 0.86 | HTR1A (0.48) | HTR1BHTR1AHDAC3BRD4HDAC4 | |
| SCHEMBL9130336 | 0.86 | DHPS (0.50) | HTR1BHDAC3BRD4HDAC4HDAC1 | |
| SCHEMBL9130728 | 0.85 | HDAC3 (0.52) | HDAC3BRD4HDAC4HDAC1HDAC7 | |
| SCHEMBL9133428 | 0.85 | DHPS (0.51) | HTR1BHDAC3BRD4HDAC4HDAC1 | |
| SCHEMBL9133110 | 0.84 | HTR1A (0.69) | HTR1BHTR1ANR2E1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL9739316 | 0.84 | DHPS (0.50) | HTR1BHDAC3BRD4HDAC4HDAC1 | |
| SCHEMBL9132132 | 0.84 | RXFP1 (0.46) | HTR1BHTR1AHDAC3BRD4HDAC4 | |
| SCHEMBL9136237 | 0.83 | DHPS (0.47) | HTR1BHDAC3BRD4HDAC4HDAC1 | |
| SCHEMBL9131204 | 0.83 | DHPS (0.47) | HTR1BHDAC3BRD4HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380722-A | Antiarrhythmia agents | ROUSSEL-UCLAF (FR) | 1995-01-10 | — | — | US | disclosed |