Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.54 |
| ▸ | SENP2 | Q9HC62 | 4/20 | 0.50 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.50 |
| ▸ | SUMO1 | P63165 | 3/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.46 |
| ▸ | CD40 | P25942 | 1/20 | 0.45 |
| ▸ | CD40LG | P29965 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17284072 | 0.86 | SENP2 (0.56) | ENPP2SENP2SUMO2SUMO1SENP7 | |
| SCHEMBL13980959 | 0.86 | CASP6 (0.47) | ENPP2SENP2SUMO2SUMO1SENP7 | |
| SCHEMBL17681933 | 0.84 | SENP2 (0.56) | ENPP2SENP2SUMO2SUMO1SENP7 | |
| SCHEMBL9626720 | 0.83 | NT5E (0.51) | ENPP2SENP2SUMO2SUMO1SENP7 | |
| SCHEMBL9809359 | 0.83 | NT5E (0.51) | ENPP2SENP2SUMO2SUMO1SENP7 | |
| SCHEMBL17460958 | 0.82 | ENPP2 (0.56) | ENPP2SENP2SUMO2SUMO1SENP7 | |
| SCHEMBL19250605 | 0.82 | CD40 (0.63) | ENPP2CD40CD40LGCASP6 | |
| SCHEMBL31149837 | 0.81 | SENP2 (0.54) | ENPP2SENP2SUMO2SUMO1SENP7 | |
| SCHEMBL8027317 | 0.81 | ENPP2 (0.55) | ENPP2SENP2SUMO2SUMO1SENP7 | |
| SCHEMBL17460973 | 0.80 | MEN1 (0.50) | ENPP2SENP2SUMO2SUMO1SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446201-A | Di(3-(2-chloroethylsulfonyl)-1-propyl)amine hydrochloride and a process for its preparation | HOECHST AG (DE) | 1995-08-29 | — | — | US | disclosed |