Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 6/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.40 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9133056 | 0.88 | ALDH1A1 (0.44) | DHPSS1PR1 | |
| SCHEMBL9129615 | 0.87 | DHPS (0.45) | DHPSS1PR1PARP1 | |
| SCHEMBL9132944 | 0.83 | AKR1C3 (0.43) | DHPSS1PR1SCN10ASCN8A | |
| SCHEMBL9130225 | 0.81 | NPC1 (0.47) | DHPSKDM1APARP1 | |
| SCHEMBL9132676 | 0.80 | DHPS (0.41) | DHPSS1PR1SCN10ASCN8APARP1 | |
| SCHEMBL9132573 | 0.80 | DHPS (0.57) | DHPSS1PR1PARP1 | |
| SCHEMBL9806178 | 0.74 | DHPS (0.60) | DHPSPARP1 | |
| SCHEMBL7884121 | 0.72 | ALDH1A1 (0.51) | CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1499352 | 0.72 | ALDH1A1 (0.51) | CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29989447 | 0.72 | ALDH1A1 (0.51) | CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380722-A | Antiarrhythmia agents | ROUSSEL-UCLAF (FR) | 1995-01-10 | — | — | US | disclosed |
| US-5084455-A | Antiarrhythmia agents for mammals | ROUSSEL UCLAF (FR) | 1992-01-28 | — | — | US | disclosed |
| US-4908367-A | Antiarrythmic agents | Uclaf, Roussel (FR) | 1990-03-13 | — | — | US | disclosed |
| US-4791109-A | Novel indole carboxamides | ROUSSEL UCLAF (FR) | 1988-12-13 | — | — | US | disclosed |