Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.47 |
| ▸ | DHPS | P49366 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129615 | 0.92 | DHPS (0.45) | NPC1MEN1KMT2AMRGPRX1DHPS | |
| SCHEMBL9450398 | 0.84 | TUBB4A (0.45) | NPC1DHPSHDAC3HDAC1ALDH1A1 | |
| SCHEMBL9129235 | 0.84 | MEN1 (0.50) | NPC1MEN1KMT2AMRGPRX1DHPS | |
| SCHEMBL9795192 | 0.83 | HSD17B10 (0.60) | NPC1MEN1KMT2AMRGPRX1DHPS | |
| SCHEMBL9131919 | 0.83 | MEN1 (0.49) | NPC1MEN1KMT2AMRGPRX1DHPS | |
| SCHEMBL9795045 | 0.81 | HDAC1 (0.50) | NPC1MEN1KMT2AMRGPRX1DHPS | |
| SCHEMBL9132310 | 0.81 | MEN1 (0.50) | NPC1MEN1KMT2AMRGPRX1DHPS | |
| SCHEMBL9132467 | 0.81 | DHPS (0.49) | DHPSKDM1APARP1 | |
| SCHEMBL9795043 | 0.81 | HDAC1 (0.52) | NPC1MEN1KMT2AMRGPRX1DHPS | |
| SCHEMBL9133056 | 0.80 | ALDH1A1 (0.44) | NPC1MEN1KMT2ADHPSHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380722-A | Antiarrhythmia agents | ROUSSEL-UCLAF (FR) | 1995-01-10 | — | — | US | disclosed |
| US-5084455-A | Antiarrhythmia agents for mammals | ROUSSEL UCLAF (FR) | 1992-01-28 | — | — | US | disclosed |
| US-4908367-A | Antiarrythmic agents | Uclaf, Roussel (FR) | 1990-03-13 | — | — | US | disclosed |
| US-4791109-A | Novel indole carboxamides | ROUSSEL UCLAF (FR) | 1988-12-13 | — | — | US | disclosed |