Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11483448 | 0.92 | MEN1 (0.31) | MEN1ALDH1A1TSHRKMT2A | |
| Potassium Ion SCHEMBL11021861 | 0.92 | — | — | |
| SCHEMBL2581393 | 0.92 | MEN1 (0.31) | MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL393085 | 0.92 | — | — | |
| SCHEMBL2043547 | 0.92 | — | — | |
| SCHEMBL2221065 | 0.92 | MEN1 (0.31) | MEN1ALDH1A1TSHRKMT2A | |
| Sulfuric Acid SCHEMBL27731326 | 0.72 | — | — | |
| Sulfuric Acid SCHEMBL3145454 | 0.71 | MEN1 (0.42) | MEN1ALDH1A1TSHRKMT2A | |
| Sulfuric Acid SCHEMBL7570890 | 0.71 | MEN1 (0.42) | MEN1ALDH1A1TSHRKMT2A | |
| Sulfuric Acid SCHEMBL16553263 | 0.71 | MEN1 (0.42) | MEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112225518-A | Mining rapid-setting high-strength reinforcing material, and preparation method and use method thereof | 陕西煤业化工技术研究院有限责任公司 | 2021-01-15 | — | — | CN | claimed |
| CN-112225518-B | Mining rapid-setting high-strength reinforcing material, and preparation method and use method thereof | 陕西煤业化工技术研究院有限责任公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-112225518-A | Mining rapid-setting high-strength reinforcing material, and preparation method and use method thereof | 陕西煤业化工技术研究院有限责任公司 | 2021-01-15 | — | — | CN | disclosed |
| EP-1948317-B1 | ANTIPERSPIRANT COMPOSITIONS | COLGATE PALMOLIVE CO (US) | 2013-10-16 | — | — | EP | disclosed |
| EP-2324815-A1 | Antiperspirant compositions | Colgate-Palmolive Company (US) | 2011-05-25 | — | — | EP | disclosed |
| US-20110014144-A1 | ANTIPERSPIRANT COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2011-01-20 | — | — | US | disclosed |
| EP-1948317-A2 | ANTIPERSPIRANT COMPOSITIONS | Colgate-Palmolive Company (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007059530-A2 | ANTIPERSPIRANT COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2007-05-24 | — | — | WO | disclosed |
| US-20070110687-A1 | Antiperspirant Compositions | COLGATE-PALMOLIVE COMPANY | 2007-05-17 | — | — | US | disclosed |