Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19283612 | 0.84 | HPD (0.47) | HPDMAPTKDM4EPOLBPDK2 | |
| SCHEMBL9711517 | 0.83 | HPD (0.46) | HPDKDM4EPDK2CES2 | |
| SCHEMBL10191434 | 0.81 | HPGD (0.50) | HPD | |
| SCHEMBL7344969 | 0.80 | TSHR (0.50) | HPDMAPTKDM4E | |
| Nitisinone SCHEMBL8423048 | 0.80 | HPD (0.75) | HPDTHRBLMNA | |
| SCHEMBL15996621 | 0.80 | HPD (0.79) | HPDMAPTKDM4ECES2 | |
| Nitisinone SCHEMBL15537279 | 0.79 | HPD (1.00) | HPDMAPTPOLBLMNA | |
| Nitisinone SCHEMBL338795 | 0.79 | HPD (1.00) | HPDMAPTPOLBLMNA | |
| Nitisinone SCHEMBL29372670 | 0.79 | HPD (1.00) | HPDMAPTPOLBLMNA | |
| SCHEMBL15133257 | 0.78 | HPD (0.42) | HPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416061-A | CONTROLLING THE GROWTH OF WEEDS | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-05-16 | — | — | US | disclosed |