Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPD | P32754 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10815118 | 0.93 | SMN1; SMN2 (0.53) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL10191434 | 0.84 | HPGD (0.50) | ALDH1A1HPD | |
| SCHEMBL9814786 | 0.84 | SMN1; SMN2 (0.47) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL15133257 | 0.84 | HPD (0.42) | HPD | |
| SCHEMBL13780019 | 0.81 | HPD (0.40) | HPD | |
| SCHEMBL9874230 | 0.81 | P2RX7 (0.49) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL10192440 | 0.80 | MAPK1 (0.46) | ALDH1A1MAPK1KDM4EMAPT | |
| SCHEMBL9711583 | 0.80 | SMN1; SMN2 (0.44) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL9134337 | 0.80 | HPD (0.64) | KDM4EMAPTHPD | |
| SCHEMBL10192439 | 0.79 | CES2 (0.48) | TSHRSMN1; SMN2ALDH1A1ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563817-A2 | Salts of 2-benzoyl-cyclohexane diones, selective herbicidal agents, process for their preparation and their use for combatting weeds | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-06 | — | — | EP | disclosed |
| EP-0090262-B1 | CERTAIN 2-(2-SUBSTITUTED BENZOYL)-1,3-CYCLOHEXANEDIONES | STAUFFER CHEMICAL COMPANY (US) | 1992-08-05 | — | — | EP | disclosed |
| US-5085688-A | Certain 2-(2-chloro-3-alkoxy-4-substituted benzoyl)-5-methyl-5-1,3-cyclohexanediones as herbicides | ICI AMERICAS INC. (US) | 1992-02-04 | — | — | US | disclosed |
| US-5006158-A | Herbicides | ICI AMERICAS INC. (US) | 1991-04-09 | — | — | US | disclosed |
| US-4957540-A | HERBICIDES | ICI AMERICAS INC. (US) | 1990-09-18 | — | — | US | disclosed |
| US-4946981-A | HERBICIDES | ICI AMERICAS INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4918236-A | HERBICIDES | ICI AMERICAS INC. (US) | 1990-04-17 | — | — | US | disclosed |
| US-4853028-A | Certain 2-(2-substituted benzoyl)-1,3-cyclohexanediones | STAUFFER CHEMICAL COMPANY (US) | 1989-08-01 | — | — | US | disclosed |
| US-4822906-A | HERBICIDE INTERMEDIATE | STAUFFER CHEMICAL COMPANY (US) | 1989-04-18 | — | — | US | disclosed |
| US-4816066-A | HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1989-03-28 | — | — | US | disclosed |
| US-4806146-A | HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1989-02-21 | — | — | US | disclosed |
| US-4780127-A | Certain 2-(substituted benzoyl)-1,3-cyclohexanediones and their use as herbicides | STAUFFER CHEMICAL COMPANY (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0137963-B1 | CERTAIN 2-(2-SUBSTITUTED BENZOYL)-1,3-CYCLOHEXANEDIONES | STAUFFER CHEMICAL COMPANY (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0253124-A2 | Certain substituted 3-(substituted oxy)-2-benzoyl-cyclohex-2-enones | STAUFFER CHEMICAL COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |
| EP-0137963-A1 | Certain 2-(2-substituted Benzoyl)-1,3-Cyclohexanediones | STAUFFER CHEMICAL COMPANY (US) | 1985-04-24 | — | — | EP | disclosed |
| EP-0090262-A2 | Certain 2-(2-substituted benzoyl)-1,3-cyclohexanediones | STAUFFER CHEMICAL COMPANY (US) | 1983-10-05 | — | — | EP | disclosed |