Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711573 | 0.86 | CES2 (0.50) | HPDPARP1PARP10SMN1; SMN2CES2 | |
| SCHEMBL9711583 | 0.83 | SMN1; SMN2 (0.44) | PARP1PARP10SMN1; SMN2JAK2JAK1 | |
| SCHEMBL9134337 | 0.83 | HPD (0.64) | HPDPDK2CES2KDM4E | |
| SCHEMBL9711453 | 0.81 | HPD (0.73) | HPDKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9711702 | 0.79 | BACE1 (0.49) | HPDPARP1PARP10CES2ALDH1A1 | |
| SCHEMBL9711637 | 0.78 | LMNA (0.32) | MEN1KMT2A | |
| SCHEMBL9711455 | 0.77 | CES2 (0.42) | CES2ALDH1A1KMT2A | |
| SCHEMBL9711491 | 0.77 | CES2 (0.49) | PARP10SMN1; SMN2CES2ALDH1A1HPGD | |
| SCHEMBL9711451 | 0.77 | LMNA (0.42) | AVPR2GPR27ALDH1A1MEN1KMT2A | |
| SCHEMBL9711657 | 0.76 | MRGPRX4 (0.42) | HPDPARP1MRGPRX4SMN1; SMN2AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |