Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136381 | 0.81 | MAOB (0.44) | MAPK1HSD17B10KDM4EMAPTMAOB | |
| SCHEMBL9134485 | 0.81 | MAOB (0.49) | ALDH1A1MAPK1PKMHSD17B10HPGD | |
| SCHEMBL7311265 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPK1PKMHSD17B10HPGD | |
| SCHEMBL12728842 | 0.69 | GPR84 (0.41) | ALDH1A1MAPK1HPGDKDM4EMAPT | |
| SCHEMBL5617596 | 0.67 | MAOB (0.67) | KDM4EMAPTMAOB | |
| SCHEMBL7291668 | 0.67 | ALDH1A1 (0.62) | ALDH1A1MAPK1PKMHSD17B10HPGD | |
| SCHEMBL5618385 | 0.63 | ALDH1A1 (0.54) | ALDH1A1MAPK1PKMHSD17B10HPGD | |
| SCHEMBL9311594 | 0.60 | ALDH1A1 (0.40) | ALDH1A1MAPK1HSD17B10HPGDTSHR | |
| SCHEMBL7301253 | 0.60 | ALDH1A1 (0.46) | ALDH1A1MAPK1PKMHSD17B10HPGD | |
| SCHEMBL9309967 | 0.59 | RAB9A (0.37) | ALDH1A1MAPK1HSD17B10HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414006-A | Monoamine oxidase inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |