SCHEMBL9136131

SCHEMBL9136131

CCCCOC(OCCCC)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 2/20 0.54
CAPN2 P17655 1/20 0.54
PSMB1 P20618 2/20 0.54
CTSK P43235 11/20 0.53
CTSS P25774 5/20 0.51
CTSL P07711 2/20 0.51
CTSB P07858 1/20 0.51
PSMB5 P28074 1/20 0.49
PSMB2 P49721 1/20 0.49
CA5A P35218 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7409367 0.99 CAPN1 (0.54) CAPN1CAPN2PSMB1CTSKCTSS
Hydrochloric Acid SCHEMBL7405797 0.91 CTSL (0.50) CTSKCTSSCTSLCTSB
Hydrochloric Acid SCHEMBL7408934 0.89 SIRT2 (0.45) CAPN1CAPN2CTSSCTSL
SCHEMBL10784684 0.84 CAPN1 (0.61) CAPN1CAPN2PSMB1CTSKCTSS
SCHEMBL10784713 0.84 CAPN1 (0.61) CAPN1CAPN2PSMB1CTSKCTSS
SCHEMBL8972241 0.84 CTSK (0.62) CAPN1CAPN2PSMB1CTSKCTSS
SCHEMBL10357511 0.84 SIRT2 (0.45) CTSSCTSL
SCHEMBL10357513 0.84 SIRT2 (0.45) CTSSCTSL
SCHEMBL10865361 0.84 SIRT2 (0.45) CTSSCTSL
SCHEMBL10357206 0.83 CA2 (0.46) CAPN1CAPN2CTSSCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5416238-A L-argininal acetal derivatives and a process for production thereof NITTO BOSEKI CO., LTD. (JP) 1995-05-16 US disclosed