SCHEMBL9136243

SCHEMBL9136243

C[N+](C)(C)Cc1ccccc1.C[N+](C)(C)Cc1ccccc1.O=C(O)c1ccc([S+]([O-])c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
KDM4E B2RXH2 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
TSHR P16473 2/20 0.46
HSD17B10 Q99714 1/20 0.46
TAS2R14 Q9NYV8 11/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SRD5A2 P31213 2/20 0.41
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
CXCR3 P49682 2/20 0.39
PTGES O14684 1/20 0.39
TAS2R8 Q9NYW2 1/20 0.39
DAO P14920 1/20 0.38
NAPRT Q6XQN6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9134432 1.00 ALDH1A1 (0.50) ALDH1A1KDM4ETDP1TSHRHSD17B10
SCHEMBL9134431 0.94 ALDH1A1 (0.45) ALDH1A1KDM4ETDP1TSHRHSD17B10
SCHEMBL9136239 0.90 ALDH1A1 (0.49) ALDH1A1KDM4ETDP1TSHRHSD17B10
Terephthalic Acid SCHEMBL8092882 0.87 ALDH1A1 (0.65) ALDH1A1KDM4ETDP1TSHRHSD17B10
Terephthalic Acid SCHEMBL8434829 0.87 ALDH1A1 (0.65) ALDH1A1KDM4ETDP1TSHRHSD17B10
SCHEMBL9134310 0.85 TSHR (0.41) ALDH1A1TSHRHSD17B10TAS2R14MEN1
SCHEMBL9134330 0.85 TSHR (0.41) ALDH1A1TSHRHSD17B10TAS2R14MEN1
Benzoic Acid SCHEMBL592072 0.84 ALDH1A1 (0.65) ALDH1A1KDM4ETDP1TSHRHSD17B10
Terephthalic Acid SCHEMBL8434830 0.83 ALDH1A1 (0.55) ALDH1A1KDM4ETDP1TSHRHSD17B10
Tetramethylammonium Ion SCHEMBL9137931 0.82 TSHR (0.50) ALDH1A1TDP1TSHRSRD5A2DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5378571-A Toners for electrography HOECHST AKTIENGESELLSCHAFT (DE) 1995-01-03 US disclosed
US-5274184-A Aryl sulphide, aryl sulphoxide and aryl sulphone compounds CASSELLA AKTIENGESELLSCHAFT (DE) 1993-12-28 US disclosed