Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.54 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976099 | 0.88 | DRD4 (0.65) | GAAKMT2ADRD2DRD4DRD3 | |
| SCHEMBL28192546 | 0.87 | CA2 (0.56) | GAAOPRM1OPRD1OPRK1 | |
| SCHEMBL2846476 | 0.83 | FFAR1 (0.68) | S1PR1S1PR3S1PR5 | |
| SCHEMBL18798799 | 0.81 | PARP10 (0.64) | LTA4H | |
| SCHEMBL10990054 | 0.81 | GAA (1.00) | TAAR1GAAMEN1KMT2ADRD2 | |
| SCHEMBL5146729 | 0.81 | TAAR1 (0.58) | TAAR1KMT2AS1PR1S1PR3S1PR5 | |
| SCHEMBL18798890 | 0.80 | FFAR1 (0.60) | S1PR1S1PR3DRD2DRD4DRD3 | |
| SCHEMBL15228875 | 0.80 | GAA (0.78) | TAAR1GAAMEN1KMT2ADRD2 | |
| SCHEMBL8976026 | 0.80 | ALOX15 (0.80) | GAA | |
| SCHEMBL8976032 | 0.80 | ALOX15 (0.80) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434184-A | B3-adrenoceptor agonist | ZENECA LIMITED (GB) | 1995-07-18 | — | — | US | disclosed |