Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9137406 | 0.85 | SLC6A4 (0.40) | MIF | |
| SCHEMBL36658 | 0.81 | NUDT1 (0.37) | ESR1ESR2NUDT1BACE1HSP90AA1 | |
| SCHEMBL29499852 | 0.81 | NUDT1 (0.37) | ESR1ESR2NUDT1BACE1HSP90AA1 | |
| SCHEMBL29372915 | 0.81 | NUDT1 (0.37) | ESR1ESR2NUDT1BACE1HSP90AA1 | |
| SCHEMBL29372576 | 0.81 | NUDT1 (0.34) | ESR1ESR2NUDT1BACE1HSP90AA1 | |
| SCHEMBL761688 | 0.81 | NUDT1 (0.34) | ESR1ESR2NUDT1BACE1HSP90AA1 | |
| SCHEMBL9135740 | 0.80 | GABRA1 (0.34) | KDM4EMEN1MAPTKMT2ANUDT1 | |
| SCHEMBL9136875 | 0.80 | MIF (0.30) | MIF | |
| SCHEMBL29484422 | 0.79 | KDM4E (0.35) | KDM4EMEN1MAPTKMT2AESR1 | |
| SCHEMBL2512536 | 0.79 | KDM4E (0.35) | KDM4EMEN1MAPTKMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401605-A | Positive working photosensitive resin composition containing 1,2-naphthoquinone diazide esterification product of triphenylmethane compound | TOKYO OHKA KOGYO CO., LTD. (JP) | 1995-03-28 | — | — | US | disclosed |