Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139159 | 0.89 | ALDH1A1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL9135606 | 0.86 | ALDH1A1 (0.35) | KEAP1NFE2L2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9136650 | 0.83 | KEAP1 (0.31) | KEAP1NFE2L2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9137791 | 0.75 | KEAP1 (0.33) | KEAP1NFE2L2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9414543 | 0.69 | KEAP1 (0.32) | KEAP1NFE2L2 | |
| SCHEMBL4082477 | 0.69 | ALDH1A1 (0.39) | ALDH1A1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL1989330 | 0.69 | ALDH1A1 (0.50) | KEAP1NFE2L2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9139057 | 0.69 | — | — | |
| SCHEMBL7749289 | 0.67 | SMN1; SMN2 (0.39) | ALDH1A1MAPK1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL10581422 | 0.67 | ALDH1A1 (0.48) | KEAP1NFE2L2ALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399674-A | Dyestuffs containing pyrimidine-carboxylic acid amide radical having fiber-reactive group, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-21 | — | — | US | disclosed |