Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018511 | 0.93 | KMT2A (0.51) | ALDH1A1MAPTP4HTMSGMS1MEN1 | |
| SCHEMBL9018298 | 0.92 | PTPN1 (0.55) | ALDH1A1MAPTP4HTMSGMS1MEN1 | |
| SCHEMBL9018302 | 0.89 | CA1 (0.50) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL9018226 | 0.89 | CA1 (0.48) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL9138015 | 0.88 | P4HTM (0.53) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL9018305 | 0.88 | BCL2L1 (0.46) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL9018261 | 0.87 | ALDH1A1 (0.45) | ALDH1A1MAPTP4HTMOPRM1OPRD1 | |
| SCHEMBL9018123 | 0.86 | OPRM1 (0.43) | ALDH1A1CA2MAPTP4HTMKMT2A | |
| SCHEMBL9018104 | 0.86 | BCL2L1 (0.48) | MAPTP4HTMMEN1KMT2AOPRM1 | |
| SCHEMBL9018237 | 0.86 | CA1 (0.55) | ALDH1A1CA1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |