Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511926 | 0.87 | ALOX15 (0.47) | ALDH1A1HPGDLMNAKDM4EL3MBTL1 | |
| SCHEMBL7506984 | 0.87 | ALOX15 (0.47) | ALDH1A1HPGDLMNAKDM4EL3MBTL1 | |
| SCHEMBL7506974 | 0.87 | ALOX15 (0.47) | ALDH1A1HPGDLMNAKDM4EL3MBTL1 | |
| SCHEMBL9140974 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HPGDCYP1A2CYP3A4GAA | |
| SCHEMBL9138241 | 0.77 | MEN1 (0.46) | ALDH1A1KDM4EL3MBTL1PGRALOX15 | |
| SCHEMBL9140727 | 0.76 | KDM4E (0.45) | ALDH1A1KDM4EL3MBTL1PGRALOX15 | |
| SCHEMBL25613272 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HPGDLMNAKDM4ECYP1A2 | |
| SCHEMBL13557668 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HPGDLMNAKDM4ECYP1A2 | |
| SCHEMBL28352194 | 0.73 | ALDH1A1 (0.41) | ALDH1A1HPGDLMNAKDM4ECYP1A2 | |
| SCHEMBL9137880 | 0.73 | GLP1R (0.46) | ALDH1A1HPGDLMNAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434148-A | β-carboline derivative | TANABE SEIYAKU CO., LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0572235-A2 | Beta-carboline derivatives with anticholecystoquinine activity | TANABE SEIYAKU CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |