Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9140727 | 0.80 | KDM4E (0.45) | MEN1KMT2AALDH1A1MAPTPGR | |
| SCHEMBL9138286 | 0.77 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1MAPTPGR | |
| SCHEMBL9137880 | 0.77 | GLP1R (0.46) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL9565146 | 0.72 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL7507129 | 0.72 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL7506984 | 0.70 | ALOX15 (0.47) | MEN1KMT2AALDH1A1MAPTPGR | |
| SCHEMBL7511926 | 0.70 | ALOX15 (0.47) | MEN1KMT2AALDH1A1MAPTPGR | |
| SCHEMBL7506974 | 0.70 | ALOX15 (0.47) | MEN1KMT2AALDH1A1MAPTPGR | |
| SCHEMBL27478508 | 0.68 | PGR (0.70) | MEN1KMT2AMAPTPGRMGLL | |
| SCHEMBL9140974 | 0.67 | ALDH1A1 (0.50) | ALDH1A1MAPK1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434148-A | β-carboline derivative | TANABE SEIYAKU CO., LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0572235-A2 | Beta-carboline derivatives with anticholecystoquinine activity | TANABE SEIYAKU CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |