Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9138367 | 0.77 | GRM4 (0.46) | HSP90AA1HSP90AB1IDO1PSMB5KDM4E | |
| SCHEMBL17112234 | 0.73 | SMN1; SMN2 (0.42) | KDM4ELMNAMAPTSMN1; SMN2CYP3A4 | |
| Phenanthroline SCHEMBL9806287 | 0.63 | CCR1 (0.84) | HSP90AA1KDM4ELMNATSHRMAPT | |
| SCHEMBL14430215 | 0.63 | GRM4 (0.43) | HSP90AA1KDM4ELMNATSHRMAPT | |
| SCHEMBL544243 | 0.63 | NCF1 (0.54) | HSP90AA1HSP90AB1IDO1PSMB5KDM4E | |
| SCHEMBL9058058 | 0.62 | KDM4E (0.50) | HSP90AA1KDM4ELMNATSHRMAPT | |
| Phenanthroline SCHEMBL28895954 | 0.61 | CCR1 (0.80) | HSP90AA1KDM4ELMNATSHRMAPT | |
| SCHEMBL6881642 | 0.61 | ALDH1A1 (0.43) | HSP90AA1HSP90AB1KDM4ELMNATSHR | |
| SCHEMBL3014296 | 0.61 | PI4KA (0.52) | PRMT5 | |
| SCHEMBL1594596 | 0.61 | ALDH1A1 (0.38) | HSP90AA1IDO1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3142638-B1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER | OREAL (FR) | 2020-08-12 | — | — | EP | disclosed |
| EP-3142638-A1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER | L'OREAL (FR) | 2017-03-22 | — | — | EP | disclosed |
| WO-2015173324-A1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER | L'OREAL (FR) | 2015-11-19 | — | — | WO | disclosed |