Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 10/20 | 0.74 |
| ▸ | MAPT | P10636 | 8/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.74 |
| ▸ | FTO | Q9C0B1 | 6/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.74 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.74 |
| ▸ | TP53 | P04637 | 4/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.74 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | XDH | P47989 | 4/20 | 0.74 |
| ▸ | POLH | Q9Y253 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | GABRP | O00591 | 3/20 | 0.74 |
| ▸ | GABRD | O14764 | 3/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31675833 | 1.00 | ABCB1 (0.74) | ABCB1MAPTCYP3A4FTOSMN1; SMN2 | |
| SCHEMBL14749128 | 0.90 | MAPT (0.73) | ABCB1MAPTCYP3A4FTOSMN1; SMN2 | |
| Chrysin SCHEMBL23530151 | 0.85 | MAPT (0.94) | ABCB1MAPTCYP3A4FTOSMN1; SMN2 | |
| Chrysin SCHEMBL29383577 | 0.85 | MAPT (1.00) | ABCB1MAPTCYP3A4FTOSMN1; SMN2 | |
| Chrysin SCHEMBL3453735 | 0.85 | MAPT (1.00) | ABCB1MAPTCYP3A4FTOSMN1; SMN2 | |
| Chrysin SCHEMBL44474 | 0.85 | MAPT (1.00) | ABCB1MAPTCYP3A4FTOSMN1; SMN2 | |
| SCHEMBL28568538 | 0.85 | CYP3A4 (0.72) | ABCB1MAPTCYP3A4FTOSMN1; SMN2 | |
| Chrysin SCHEMBL10809371 | 0.84 | MAPT (0.97) | ABCB1MAPTCYP3A4FTOSMN1; SMN2 | |
| Chrysin SCHEMBL29183306 | 0.84 | MAPT (0.97) | ABCB1MAPTCYP3A4FTOSMN1; SMN2 | |
| Chrysin SCHEMBL28879361 | 0.84 | MAPT (0.97) | ABCB1MAPTCYP3A4FTOSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110038960-A1 | PREPARATION AND USE OF A PLANT EXTRACT FROM SOLANUM GLAUCOPHYLLUM WITH AN ENRICHED CONTENT OF 1,25-DIHYDROXYVITAMIN D3 GLYCOSIDES AND QUERCETIN GLYCOSIDES | HERBONIS AG (CH) | 2011-02-17 | — | — | US | claimed |
| EP-2265277-A1 | PREPARATION AND USE OF A PLANT EXTRACT FROM SOLANUM GLAUCOPHYLLUM WITH AN ENRICHED CONTENT OF 1,25-DIHYDROXYVITAMIN D3 GLYCOSIDES AND QUERCETIN GLYCOSIDES | Herbonis Ag (CH) | 2010-12-29 | — | — | EP | claimed |
| WO-2009129818-A1 | PREPARATION AND USE OF A PLANT EXTRACT FROM SOLANUM GLAUCOPHYLLUM WITH AN ENRICHED CONTENT OF 1,25-DIHYDROXYVITAMIN D3 GLYCOSIDES AND QUERCETIN GLYCOSIDES | HERBONIS AG (CH) | 2009-10-29 | — | — | WO | claimed |
| WO-2009130005-A2 | PREPARATION AND USE OF A PLANT EXTRACT FROM SOLANUM GLAUCOPHYLLUM WITH AN ENRICHED CONTENT OF 1,25-DIHYDROXYVITAMIN D3 GLYCOSIDES AND QUERCETIN GLYCOSIDES | HERBONIS AG (CH) | 2009-10-29 | — | — | WO | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| EP-0263553-A2 | Method of inhibiting gene induction | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-04-13 | — | — | EP | claimed |
| US-20250263774-A1 | DISCOVERING NEW XENOBIOTIC SUBSTRATES OF AN UDP-GLYCOSYLTRANSFERASE WITH A HIGH-THROUGHPUT METHOD | UNIV NORTH TEXAS (US) | 2025-08-21 | — | — | US | disclosed |
| EP-3139938-B1 | A MATRIX-METALLOPROTEINASE (MMP) INHIBITORY EXTRACT AND METHODS OF USE THEREOF | COMVITA LTD (NZ) | 2020-04-01 | — | — | EP | disclosed |
| EP-2265277-B1 | PREPARATION AND USE OF A PLANT EXTRACT FROM SOLANUM GLAUCOPHYLLUM WITH AN ENRICHED CONTENT OF 1,25-DIHYDROXYVITAMIN D3 GLYCOSIDES AND QUERCETIN GLYCOSIDES | HERBONIS AG (CH) | 2018-10-03 | — | — | EP | disclosed |
| EP-2730431-B1 | Rubber composition and tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2017-06-28 | — | — | EP | disclosed |
| US-9446088-B2 | Preparation and use of a plant extract from solanum glaucophyllum with an enriched content of 1,25 dihydroxyvitamin D3 glycosides and quercetin glycosides | HERBONIS AG (CH) | 2016-09-20 | — | — | US | disclosed |
| US-20140135433-A1 | TIRE WITH RUBBER CONTAINING FLAVONE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2014-05-15 | — | — | US | disclosed |
| EP-2730431-A1 | Rubber composition and tire with rubber containing flavone | The Goodyear Tire & Rubber Company (US) | 2014-05-14 | — | — | EP | disclosed |
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | EASTMAN CHEMICAL COMPANY | 2007-11-01 | — | — | US | disclosed |
| WO-2007115181-A2 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEMICAL COMPANY (US) | 2007-10-11 | — | — | WO | disclosed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
| EP-0263553-A2 | Method of inhibiting gene induction | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | ABCC4, NCOA4, NR4A3 | ABCB1 59/4885MAPT 4566/4885CYP3A4 17/4885 |
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | ABCB1 2498/4885MAPT 4313/4885CYP3A4 3010/4885 |
| US-20110038960-A1 | PREPARATION AND USE OF A PLANT EXTRACT FROM SOLANUM GLAUCOPHYLLUM WITH AN ENRICHED CONTENT OF 1,25-DIHYDROXYVITAMIN D3 GLYCOSIDES AND QUERCETIN GLYCOSIDES | CYP27B1, SYVN1, CYP24A1 | ABCB1 3509/4885MAPT 2566/4885CYP3A4 2410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.