Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 2/20 | 0.65 |
| ▸ | TNKS | O95271 | 1/20 | 0.65 |
| ▸ | PARP1 | P09874 | 1/20 | 0.65 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.65 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.65 |
| ▸ | CCNC | P24863 | 1/20 | 0.57 |
| ▸ | CDK8 | P49336 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | RAF1 | P04049 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31303695 | 0.89 | CYP3A4 (0.67) | ARADORA3MAOBTNKSPARP1 | |
| SCHEMBL9138573 | 0.89 | CYP3A4 (0.67) | ARADORA3MAOBTNKSPARP1 | |
| SCHEMBL1645772 | 0.84 | AR (0.54) | ARADORA3CYP3A4MAPTMEN1 | |
| SCHEMBL12636899 | 0.84 | AR (1.00) | ARMAOBTNKSPARP1TNKS2 | |
| SCHEMBL12378900 | 0.82 | MAPT (0.76) | ARMAOBTNKSPARP1TNKS2 | |
| SCHEMBL9137273 | 0.82 | AR (0.80) | ARADORA3MAOBTNKSPARP1 | |
| SCHEMBL31060888 | 0.79 | ADORA3 (1.00) | ARADORA3MAOBTNKSPARP1 | |
| SCHEMBL7593917 | 0.79 | TNKS (1.00) | ARADORA3MAOBTNKSPARP1 | |
| SCHEMBL16521506 | 0.77 | ADORA3 (0.69) | ARADORA3MAOBTNKSPARP1 | |
| SCHEMBL7606268 | 0.77 | PTGS2 (0.61) | ARADORA3MAOBTNKSPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023079362-A1 | PROCESSABLE COMPOSITIONS AND USE FOR THE SAME | RIPPLE THERAPEUTICS CORPORATION (CA) | 2023-05-11 | — | — | WO | disclosed |