Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.51 |
| ▸ | MME | P08473 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9140461 | 0.86 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL7839345 | 0.84 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9010408 | 0.78 | AGTR2 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9279927 | 0.77 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9142986 | 0.76 | AGTR1 (0.51) | AGTR1AGTR2MME | |
| SCHEMBL8636053 | 0.75 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL7839692 | 0.74 | AGTR2 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9010373 | 0.74 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9010365 | 0.73 | AGTR1 (0.51) | AGTR1AGTR2MME | |
| SCHEMBL8634380 | 0.73 | AGTR2 (0.45) | AGTR1AGTR2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420149-A | Hypotensive agents and artheriosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-30 | — | — | US | claimed |