Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30445378 | 0.85 | MTNR1A (0.45) | MTNR1AMTNR1BMAOAMAOBFFAR1 | |
| SCHEMBL6753024 | 0.85 | HTR1D (0.39) | MTNR1AMTNR1B | |
| SCHEMBL3128725 | 0.82 | MTNR1A (0.39) | MTNR1AMTNR1B | |
| SCHEMBL23391660 | 0.81 | MTNR1A (0.43) | MTNR1AMTNR1BALDH1A1TSHRHTT | |
| SCHEMBL4192714 | 0.78 | ALDH1A1 (0.36) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL20671290 | 0.78 | MTNR1A (0.46) | MTNR1AMTNR1BMAOAMAOBFFAR1 | |
| SCHEMBL285609 | 0.78 | MTNR1A (0.36) | MTNR1AMTNR1BELANEALDH1A1TSHR | |
| Methacrylic Acid SCHEMBL28837351 | 0.77 | MTNR1A (0.43) | MTNR1AMTNR1BMAOAMAOBALDH1A1 | |
| SCHEMBL7529592 | 0.77 | MTNR1A (0.43) | MTNR1AMTNR1BFFAR1ELANEALDH1A1 | |
| SCHEMBL720462 | 0.77 | ELANE (0.35) | MTNR1AMTNR1BFFAR1ELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160194424-A1 | MONOMERS FOR USE IN A POLYMERIZABLE COMPOSITION AND HIGH REFRACTIVE INDEX POLYMER FOR OPTHALMIC APPLICATIONS | CONTAMAC LIMITED (GB) | 2016-07-07 | — | — | US | disclosed |
| US-20160002144-A1 | HIGH REFRACTIVE INDEX POLYMER COMPOSITION FOR OPTHALMIC APPLICATIONS | CONTAMAC LTD (GB) | 2016-01-07 | — | — | US | disclosed |
| US-9103964-B2 | Intraocular lenses essentially free from glistenings | OCULENTIS HOLDING B.V. (NL) | 2015-08-11 | — | — | US | disclosed |
| US-8759414-B2 | Polymer composition having a high refractive index | CORONIS GMBH (DE) | 2014-06-24 | — | — | US | disclosed |
| US-8759414-B2 | Polymer composition having a high refractive index | CORONIS GMBH (DE) | 2014-06-24 | — | — | US | disclosed |
| US-20130035414-A1 | HIGH REFRACTIVE INDEX POLYMER COMPOSITION FOR OPTHALMIC APPLICATIONS | CONTAMAC LIMITED (GB) | 2013-02-07 | — | — | US | disclosed |
| EP-1984761-B1 | INTRAOCULAR LENSES ESSENTIALLY FREE FROM GLISTENINGS | PROCORNEA HOLDING BV (NL) | 2011-03-23 | — | — | EP | disclosed |
| US-20110021733-A1 | INTRAOCULAR LENSES ESSENTIALLY FREE FROM GLISTENINGS | PROCORNEA HOLDING B.V. | 2011-01-27 | — | — | US | disclosed |
| US-20090247661-A1 | POLYMER COMPOSITION HAVING A HIGH REFRACTIVE INDEX | CORONIS GMBH (DE) | 2009-10-01 | — | — | US | disclosed |
| US-20090247661-A1 | POLYMER COMPOSITION HAVING A HIGH REFRACTIVE INDEX | CORONIS GMBH (DE) | 2009-10-01 | — | — | US | disclosed |
| US-20090054978-A1 | INTRAOCULAR LENSES ESSENTIALLY FREE FROM GLISTENINGS | PROCOMEA HOLDING B.V. | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035414-A1 | HIGH REFRACTIVE INDEX POLYMER COMPOSITION FOR OPTHALMIC APPLICATIONS | NR1I3, NR1I2, LBR | MTNR1A 538/4885MTNR1B 1016/4885MAOA 3365/4885 |
| US-20160002144-A1 | HIGH REFRACTIVE INDEX POLYMER COMPOSITION FOR OPTHALMIC APPLICATIONS | NR1I3, NR1I2, LBR | MTNR1A 311/4885MTNR1B 692/4885MAOA 3402/4885 |
| US-20160194424-A1 | MONOMERS FOR USE IN A POLYMERIZABLE COMPOSITION AND HIGH REFRACTIVE INDEX POLYMER FOR OPTHALMIC APPLICATIONS | NR2E3, NR1I2, NR1I3 | MTNR1A 100/4885MTNR1B 161/4885MAOA 2847/4885 |
| US-20090247661-A1 | POLYMER COMPOSITION HAVING A HIGH REFRACTIVE INDEX | RPIA, PDE6D, PDE6A | MTNR1A 2953/4885MTNR1B 3460/4885MAOA 3485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.