Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392777 | 0.80 | ELANE (0.41) | MTNR1AMTNR1BELANEKDM4EALDH1A1 | |
| SCHEMBL914115 | 0.78 | MTNR1A (0.49) | MTNR1AMTNR1BELANEALDH1A1TSHR | |
| SCHEMBL8038661 | 0.75 | PPARG (0.39) | ELANEKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL6271230 | 0.75 | ELANE (0.37) | MTNR1AMTNR1BELANEKDM4EALDH1A1 | |
| SCHEMBL15864415 | 0.75 | ALPI (0.40) | ELANEALDH1A1PKMTSHR | |
| SCHEMBL10907558 | 0.75 | HCAR2 (0.53) | ELANEALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL41864 | 0.75 | HCAR2 (0.53) | ELANEALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL720462 | 0.73 | ELANE (0.35) | MTNR1AMTNR1BELANEALDH1A1MAPT | |
| Ethylene Glycol SCHEMBL6490841 | 0.73 | HCAR2 (0.47) | ELANEALDH1A1 | |
| SCHEMBL4596085 | 0.72 | ALDH1A1 (0.40) | MTNR1AMTNR1BELANEALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427509-A1 | POLYMER COMPOSITION | Contamac Limited (GB) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128266-A1 | POLYMER COMPOSITION | CONTAMAC LIMITED (GB) | 2010-11-11 | — | — | WO | disclosed |