Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28701891 | 0.87 | F10 (0.66) | F10RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL20022682 | 0.83 | RAB9A (0.59) | F10RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL9682543 | 0.79 | KCNMA1 (0.65) | RAB9ASMN1; SMN2NPC1HPGDPKM | |
| SCHEMBL8060238 | 0.79 | NPC1 (0.75) | F10RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL31092076 | 0.75 | HPGD (0.68) | RAB9ASMN1; SMN2NPC1HPGDLMNA | |
| SCHEMBL29168826 | 0.75 | RAB9A (0.73) | RAB9ASMN1; SMN2NPC1ALDH1A1MEN1 | |
| SCHEMBL30758595 | 0.75 | RAB9A (0.73) | RAB9ASMN1; SMN2NPC1ALDH1A1MEN1 | |
| SCHEMBL28695522 | 0.74 | KMT2A (0.70) | RAB9ASMN1; SMN2NPC1HPGDLMNA | |
| SCHEMBL27732526 | 0.73 | TDP1 (0.53) | RAB9ASMN1; SMN2NPC1HPGDPKM | |
| SCHEMBL5130336 | 0.72 | RAB9A (0.54) | RAB9ASMN1; SMN2NPC1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420292-A | Biphenyl-tetrazole intermediate compounds | ZENECA LIMITED (GB) | 1995-05-30 | — | — | US | disclosed |
| US-5294716-A | Chemical process for making angiotesin II antagonist compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-03-15 | — | — | US | disclosed |