Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.47 |
| ▸ | SELE | P16581 | 2/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9146301 | 0.89 | ICAM1 (0.58) | L3MBTL1ICAM1SELEVCAM1SMN1; SMN2 | |
| SCHEMBL9146163 | 0.88 | KDM4E (0.48) | L3MBTL1ICAM1SELEVCAM1SMN1; SMN2 | |
| SCHEMBL9144156 | 0.87 | ICAM1 (0.55) | L3MBTL1ICAM1SELEVCAM1SMN1; SMN2 | |
| SCHEMBL9534704 | 0.82 | KDM4E (0.53) | ICAM1SELESMN1; SMN2MAPTMEN1 | |
| Guanidine SCHEMBL8693373 | 0.81 | ICAM1 (0.44) | L3MBTL1ICAM1SELEVCAM1SMN1; SMN2 | |
| SCHEMBL5659192 | 0.80 | L3MBTL1 (0.55) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9142199 | 0.79 | L3MBTL1 (0.48) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9539011 | 0.79 | MPO (0.44) | ICAM1SELEVCAM1SMN1; SMN2POLB | |
| SCHEMBL6656226 | 0.78 | L3MBTL1 (0.45) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9142952 | 0.78 | L3MBTL1 (0.47) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186367-B1 | ACIDIC INDOLE COMPOUNDS AND THEIR USE AS ANTIALLERGY AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-03-03 | — | — | EP | disclosed |
| US-4675332-A | Acidic tetrazolyl substituted indole compounds and their use as antiallergy agents | WARNER-LAMBERT COMPANY (US) | 1987-06-23 | — | — | US | disclosed |
| EP-0186367-A2 | Acidic indole compounds and their use as antiallergy agents | WARNER-LAMBERT COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |