Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17724573 | 0.87 | KDM4E (0.54) | MAPK1KDM4EHIF1ATSHRALDH1A1 | |
| SCHEMBL3690640 | 0.80 | MTNR1A (0.32) | MTNR1AMTNR1B | |
| SCHEMBL28780810 | 0.75 | ZDHHC20 (0.47) | MAPK1TSHRALDH1A1MTNR1AMTNR1B | |
| SCHEMBL8107 | 0.71 | KDM4E (0.71) | MAPK1KDM4EHIF1ATSHRALDH1A1 | |
| SCHEMBL25639567 | 0.70 | EPHX1 (0.53) | TSHR | |
| SCHEMBL209638 | 0.69 | — | — | |
| SCHEMBL5463166 | 0.69 | KDM4E (0.52) | MAPK1KDM4EHIF1ATSHRALDH1A1 | |
| SCHEMBL14081541 | 0.68 | EPHX1 (0.34) | MAPK1KDM4EHIF1ATSHRALDH1A1 | |
| SCHEMBL23458368 | 0.67 | EPHX1 (0.40) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL3407201 | 0.67 | TSHR (0.57) | MAPK1KDM4EHIF1ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193293-B2 | Low temperature curable coating compositions and related methods | PPG INDUSTRIES OHIO, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| US-7868116-B2 | Process for the production of high-molecular-weight organopolysiloxanes | WACKER CHEMIE AG (DE) | 2011-01-11 | — | — | US | disclosed |
| EP-2257607-A1 | LOW TEMPERATURE CURABLE COATING COMPOSITIONS AND RELATED METHODS | PPG Industries Ohio, Inc. (US) | 2010-12-08 | — | — | EP | disclosed |
| US-7834121-B2 | alkoxy-endcapped polysiloxane, epoxy-functional polysiloxane and an aminosilane curing agent; coating flexibility, hardness, impact resistance, corrosion resistance and/or chemical resistance with improved weatherability; fast-curing; without need for acrylates; reduced volatile organic content | PPG INDUSTRIES OHIO, INC. (US) | 2010-11-16 | — | — | US | disclosed |
| EP-2137274-A2 | SILICONE RESIN CONTAINING COATING COMPOSITIONS, RELATED COATED SUBSTRATES AND METHODS | PPG Industries Ohio, Inc. (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2009117237-A1 | LOW TEMPERATURE CURABLE COATING COMPOSITIONS AND RELATED METHODS | PPG INDUSTRIES OHIO, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| US-20090234071-A1 | LOW TEMPERATURE CURABLE COATING COMPOSITIONS AND RELATED METHODS | PPG INDUSTRIES OHIO, INC. (US) | 2009-09-17 | — | — | US | disclosed |
| US-7582700-B2 | Method for the production of emulsions of highly-viscous organopolysiloxanes | WACKER CHEMIE AG (DE) | 2009-09-01 | — | — | US | disclosed |
| US-20090198034-A1 | PROCESS FOR THE PRODUCTION OF HIGH-MOLECULAR-WEIGHT ORGANOPOLYSILOXANES | WACKER CHEMIE AG (DE) | 2009-08-06 | — | — | US | disclosed |
| WO-2008121528-A2 | SILICONE RESIN CONTAINING COATING COMPOSITIONS, RELATED COATED SUBSTRATES AND METHODS | PPG INDUSTRIES OHIO, INC. (US) | 2008-10-09 | — | — | WO | disclosed |
| US-20080064813-A1 | METHOD FOR PRODUCING CROSSLINKABLE ORGANOPOLYSILOXANE DISPERSIONS | WACKER CHEMIE AG (DE) | 2008-03-13 | — | — | US | disclosed |
| US-20080033062-A1 | Method for the Production of Emulsions of Highly-Viscous Organopolysiloxanes | WACKER CHEMIE AG (DE) | 2008-02-07 | — | — | US | disclosed |
| US-20070213492-A1 | SILICONE RESIN CONTAINING COATING COMPOSITIONS, RELATED COATED SUBSTRATES AND METHODS | PPG INDUSTRIES OHIO, INC. | 2007-09-13 | — | — | US | disclosed |
| US-20060258820-A1 | Process for preparing dispersions of crosslinked organopolysiloxanes | WACKER CHEMIE AG (DE) | 2006-11-16 | — | — | US | disclosed |
| US-7126020-B2 | Reactions rapidly complete or proceeds at low temperature such as room temperature; highly viscous and stable products with Si C-bonded radicals containing basic nitrogen | WACKER CHEMIE AG (DE) | 2006-10-24 | — | — | US | disclosed |
| US-20050131243-A1 | Process for preparing highly viscous organopolysiloxanes | WACKER-CHEMIE GMBH (DE) | 2005-06-16 | — | — | US | disclosed |