Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407248 | 0.86 | TSHR (0.61) | TSHRKDM4EMAPK1HIF1AEPHX2 | |
| SCHEMBL15146916 | 0.85 | TSHR (0.46) | TSHRCA12CA14KDM4EMAPK1 | |
| SCHEMBL14507335 | 0.84 | KDM4E (0.62) | TSHRKDM4EMAPK1HIF1AEPHX2 | |
| SCHEMBL130413 | 0.82 | KDM4E (0.67) | TSHRKDM4EMAPK1HIF1AEPHX2 | |
| SCHEMBL23940007 | 0.81 | KDM4E (0.46) | TSHRCA12CA14KDM4EMAPK1 | |
| SCHEMBL9683695 | 0.80 | TSHR (0.57) | TSHRCA12CA14KDM4EEPHX2 | |
| SCHEMBL13813999 | 0.80 | TSHR (0.57) | TSHRCA12CA14KDM4EEPHX2 | |
| SCHEMBL48439 | 0.79 | GAA (0.52) | TSHRKDM4EMAPK1HIF1AMGAM | |
| SCHEMBL14902247 | 0.79 | MGAM (0.52) | TSHRCA12CA14KDM4EEPHX2 | |
| SCHEMBL860790 | 0.79 | KDM4E (0.56) | TSHRKDM4EMAPK1HIF1AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261216-A2 | Pyrazoles as glucokinase activators | F. Hoffmann-La Roche AG (CH) | 2010-12-15 | — | — | EP | claimed |
| EP-2046755-A2 | PYRAZOLES AS GLUCOKINASE ACTIVATORS | F. Hoffmann-Roche AG (CH) | 2009-04-15 | — | — | EP | claimed |
| WO-2008012227-A2 | PYRAZOLES AS GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-01-31 | — | — | WO | claimed |
| US-20080021032-A1 | Pyrazole glucokinase activators | BERTHEL STEVEN JOSEPH | 2008-01-24 | — | — | US | claimed |
| WO-2006119283-A2 | ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE | YU RUEY J (US) | 2006-11-09 | — | — | WO | claimed |
| US-20060251597-A1 | ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE | YU RUEY J | 2006-11-09 | — | — | US | claimed |
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2024-02-29 | — | — | US | disclosed |
| US-11772063-B2 | Method and device for producing saccharides and saccharide arrays | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-10-03 | — | — | US | disclosed |
| US-11534419-B2 | N-acetyl beta alanine methods of use | THERMOLIFE INTERNATIONAL, LLC (US) | 2022-12-27 | — | — | US | disclosed |
| US-11534419-B2 | N-acetyl beta alanine methods of use | THERMOLIFE INTERNATIONAL, LLC (US) | 2022-12-27 | — | — | US | disclosed |
| US-11168104-B2 | Unique self-assembled poly-amidoamine polymers and their eletrochemical reactivity | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-11-09 | — | — | US | disclosed |
| WO-2020127391-A1 | METHOD AND DEVICE FOR PRODUCING SACCHARIDES AND SACCHARIDE ARRAYS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2020-06-25 | — | — | WO | disclosed |
| US-20200062757-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2020-02-27 | — | — | US | disclosed |
| WO-2008012227-A2 | PYRAZOLES AS GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-01-31 | — | — | WO | disclosed |
| US-7276601-B2 | Method and preparing fused oxazinones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-02 | — | — | US | disclosed |
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | disclosed |
| US-20060251597-A1 | ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE | YU RUEY J | 2006-11-09 | — | — | US | disclosed |
| US-5173510-A | Anticholesterol agents | AMERICAN CYANAMID COMPANY (US) | 1992-12-22 | — | — | US | disclosed |
| US-5053426-A | Enzyme inhibitors | AMERICAN CYANAMID COMPANY (US) | 1991-10-01 | — | — | US | disclosed |
| EP-0409413-A2 | Diaryl ether heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11772063-B2 | Method and device for producing saccharides and saccharide arrays | MGAM, SORD, FUT5 | TSHR 2381/4885CA12 67/4885CA14 41/4885 |
| US-20200062757-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | TSHR 477/4885CA12 34/4885CA14 44/4885 |
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | TSHR 477/4885CA12 34/4885CA14 44/4885 |
| US-11168104-B2 | Unique self-assembled poly-amidoamine polymers and their eletrochemical reactivity | EPM2A, PAM, CCNA1 | TSHR 3598/4885CA12 168/4885CA14 343/4885 |
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | MAPK1, MAPK3, MAPK4 | TSHR 1602/4885CA12 4569/4885CA14 4355/4885 |
| US-11534419-B2 | N-acetyl beta alanine methods of use | AADAT, B3GNT2, AANAT | TSHR 3703/4885CA12 846/4885CA14 808/4885 |
| US-20080021032-A1 | Pyrazole glucokinase activators | GCKR, GCK, GALK1 | TSHR 2577/4885CA12 4798/4885CA14 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.