Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HEXA | P06865 | 1/20 | 0.43 |
| ▸ | HEXB | P07686 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 3/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.39 |
| ▸ | WNT3A | P56704 | 2/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7248333 | 0.87 | GFER (0.46) | RAB9AGFERKDM4ENPC1POLB | |
| SCHEMBL9422993 | 0.84 | RAB9A (0.41) | RAB9AGFERKDM4ENPC1POLB | |
| SCHEMBL2821562 | 0.81 | KDM4E (0.39) | RAB9AKDM4ENPC1POLBTNKS | |
| SCHEMBL20853413 | 0.79 | RAB9A (0.48) | RAB9AGFERKDM4ENPC1POLB | |
| SCHEMBL17803376 | 0.79 | RAB9A (0.48) | RAB9AGFERKDM4ENPC1POLB | |
| SCHEMBL8797359 | 0.77 | GFER (0.50) | RAB9AGFERKDM4ENPC1POLB | |
| SCHEMBL7486822 | 0.77 | ALDH1A1 (0.39) | RAB9AGFERKDM4ENPC1POLB | |
| SCHEMBL2780530 | 0.77 | POLB (0.41) | RAB9AKDM4ENPC1POLBCXCR2 | |
| SCHEMBL20853414 | 0.74 | RAB9A (0.41) | RAB9AGFERKDM4ENPC1POLB | |
| SCHEMBL2652520 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378847-A | Cyclization by forming a bond between carbon and nitrogen, reaction with formaldehyde and amine | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1995-01-03 | — | — | US | disclosed |
| US-5296609-A | Antiischemic agents | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1994-03-22 | — | — | US | disclosed |