Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9141467 | 0.81 | NOX1 (0.43) | NOX1UGT2B7MEN1TSHRKMT2A | |
| SCHEMBL9143998 | 0.75 | UGT2B7 (0.36) | NOX1UGT2B7MEN1TSHRKMT2A | |
| SCHEMBL9419052 | 0.74 | UGT2B7 (0.35) | NOX1UGT2B7MEN1TSHRKMT2A | |
| SCHEMBL31085264 | 0.72 | RXRA (0.41) | NOX1UGT2B7 | |
| SCHEMBL31003100 | 0.71 | RXRA (0.40) | UGT2B7MEN1TSHRKMT2A | |
| SCHEMBL9147995 | 0.71 | RXRA (0.38) | NOX1UGT2B7MEN1TSHRKMT2A | |
| SCHEMBL9418988 | 0.71 | HTR2A (0.33) | UGT2B7 | |
| SCHEMBL25668108 | 0.68 | RECQL (0.33) | TSHRKMT2A | |
| SCHEMBL10557217 | 0.68 | RARA (0.45) | NOX1UGT2B7KMT2A | |
| SCHEMBL31085011 | 0.68 | KMT2A (0.36) | UGT2B7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350846-B1 | Condensed heterocyclic compounds and their use in therapy | HOFFMANN LA ROCHE (CH) | 1995-10-11 | — | — | EP | disclosed |
| US-5420273-A | Skin disorders and antitumor agents | HOFFMAN-LA ROCHE INC. (US) | 1995-05-30 | — | — | US | disclosed |
| US-5300522-A | Treating inflammatory, allergic, rheumatic, immunological disorders | HOFFMANN-LA ROCHE INC. (US) | 1994-04-05 | — | — | US | disclosed |
| US-5164387-A | Antitumor agents, skin disorders, antiinflammatory agents | HOFFMANN-LAROCHE INC. (US) | 1992-11-17 | — | — | US | disclosed |
| US-5037825-A | Useful In The Treatment Of Neoplasms, Dermatoses And Aging Of The Skin | HOFFMANN-LA ROCHE INC. (US) | 1991-08-06 | — | — | US | disclosed |
| EP-0350846-A2 | Condensed heterocyclic compounds and their use in therapy | F. HOFFMANN-LA ROCHE AG (CH) | 1990-01-17 | — | — | EP | disclosed |