SCHEMBL9145170

SCHEMBL9145170

CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(S(=O)(=O)NC(=O)c2ccccc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9145972 0.89 AGTR1 (0.81) AGTR1
SCHEMBL9143545 0.83 AGTR1 (0.74) AGTR1
SCHEMBL9591469 0.80 EDNRA (0.49) AGTR1
SCHEMBL9032695 0.80
SCHEMBL9034225 0.79 AGTR1 (0.55) AGTR1
SCHEMBL9032504 0.79 EDNRA (0.70) AGTR1
L-159913 SCHEMBL9144158 0.78 AGTR1 (1.00) AGTR1
SCHEMBL9144349 0.78 AGTR1 (0.70) AGTR1
SCHEMBL14860678 0.78 AGTR2 (0.54)
SCHEMBL9032026 0.77 AGTR1 (0.72) AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5411980-A Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin II antagonists MERCK & CO., INC. (US) 1995-05-02 US disclosed