Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6061977 | 0.91 | PDE4B (0.58) | PDE4BKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9145008 | 0.90 | PDE4B (0.43) | PDE4BALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL41599 | 0.81 | SCN9A (0.47) | PDE4BHPGDSCN9ACNR1CNR2 | |
| SCHEMBL9143114 | 0.76 | PDE4B (0.51) | PDE4BALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL8997635 | 0.74 | HTT (0.51) | MEN1KMT2AHPGDLMNANPC1 | |
| SCHEMBL1395234 | 0.73 | KDM4E (0.51) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL7951802 | 0.73 | PRKCZ (0.52) | LMNAMCHR1NPC1RAB9APTGDR2 | |
| SCHEMBL14218538 | 0.71 | SCN9A (0.45) | PDE4BSCN9AMCHR1PTGDR2TBXA2R | |
| SCHEMBL27390460 | 0.71 | PDE4B (0.46) | PDE4BKDM4EALDH1A1KMT2ASCN9A | |
| SCHEMBL8997771 | 0.70 | PDE4B (0.49) | PDE4BKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459262-A | Process for the preparation of phenylbenzamide derivatives | RHONE-POULENC AGROCHIMIE (FR) | 1995-10-17 | — | — | US | disclosed |
| EP-0611232-A1 | Process for the preparation of phenylbenzamide derivatives | RHONE-POULENC AGROCHIMIE (FR) | 1994-08-17 | — | — | EP | disclosed |