SCHEMBL8997635

SCHEMBL8997635

CCOC(=O)c1ccc(C(F)(F)F)cc1-c1ccc(OC)c(OC)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.51
MAPT P10636 6/20 0.47
PTGDR2 Q9Y5Y4 1/20 0.46
TUBB4A P04350 1/20 0.46
TUBB P07437 1/20 0.46
TUBA3C P0DPH7 1/20 0.46
TUBA1B P68363 1/20 0.46
TUBA4A P68366 1/20 0.46
TUBB4B P68371 1/20 0.46
TUBB3 Q13509 1/20 0.46
TUBB2A Q13885 1/20 0.46
TUBB8 Q3ZCM7 1/20 0.46
TUBA3E Q6PEY2 1/20 0.46
TUBA1A Q71U36 1/20 0.46
TUBA1C Q9BQE3 1/20 0.46
TUBB6 Q9BUF5 1/20 0.46
TUBB2B Q9BVA1 1/20 0.46
TUBB1 Q9H4B7 1/20 0.46
LMNA P02545 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1395234 0.84 KDM4E (0.51) MAPTPTGDR2LMNAMEN1KMT2A
SCHEMBL7951802 0.82 PRKCZ (0.52) MAPTPTGDR2LMNANPC1PRKCZ
SCHEMBL6061977 0.82 PDE4B (0.58) PTGDR2LMNAMEN1KMT2AHPGD
SCHEMBL7980488 0.82 HTT (0.60) HTTMAPTTUBB4ATUBBTUBA3C
SCHEMBL8759774 0.82 MAPT (0.55) HTTMAPTTUBB4ATUBBTUBA3C
SCHEMBL8759768 0.81 HTT (0.54) HTTMAPTTUBB4ATUBBTUBA3C
SCHEMBL9181819 0.81 TUBB4A (0.55) HTTMAPTTUBB4ATUBBTUBA3C
SCHEMBL41599 0.81 SCN9A (0.47) MAPTPTGDR2HPGD
SCHEMBL7984003 0.80 ERN1 (0.65) HTTMAPTTUBB4ATUBBTUBA3C
SCHEMBL30740971 0.78 TUBB4A (0.49) HTTMAPTTUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5514719-A Fungicidal phenylbenzamides RHONE-POULENC AGROCHIMIE (FR) 1996-05-07 US disclosed