Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.55 |
| ▸ | RARB | P10826 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152382 | 0.88 | L3MBTL1 (0.46) | TP53TSHRMAPTALDH1A1 | |
| SCHEMBL9445473 | 0.82 | PLA2G4B (0.56) | TP53TSHRPLA2G4BMAPTPTPN11 | |
| SCHEMBL7271274 | 0.79 | TP53 (0.90) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL2839058 | 0.79 | CNR2 (0.52) | TSHRMAPTALDH1A1 | |
| SCHEMBL2844258 | 0.76 | CNR2 (0.50) | TP53TSHRMAPTALDH1A1 | |
| SCHEMBL2842661 | 0.76 | CNR2 (0.50) | TSHRMAPTALDH1A1 | |
| SCHEMBL2846352 | 0.76 | CNR2 (0.50) | TSHRMAPTALDH1A1 | |
| SCHEMBL2848554 | 0.76 | CNR2 (0.50) | TSHRMAPTALDH1A1 | |
| SCHEMBL17215244 | 0.75 | TSHR (0.48) | TP53TSHRPLA2G4BPTPN11ALDH1A1 | |
| SCHEMBL9513077 | 0.75 | ALDH1A1 (0.59) | TP53TSHRPLA2G4BRARBPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442748-B1 | Improvements in and relating to leukotriene antagonists | LILLY CO ELI (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0442748-A1 | Improvements in and relating to leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1991-08-21 | — | — | EP | disclosed |
| US-4996230-A | Antiallergens, antiinflammatory agent | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |