SCHEMBL9147199

SCHEMBL9147199

O=C(Nc1cccc(C(=O)O)c1O)OCc1ccc(Cl)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.55
ALDH1A1 P00352 2/20 0.51
KDM4E B2RXH2 1/20 0.51
LMNA P02545 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
GAA P10253 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
CASP3 P42574 3/20 0.44
CASR P41180 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8115672 0.89 ALDH1A1 (0.63) ALDH1A1KDM4ELMNASMN1; SMN2NPC1
SCHEMBL9151220 0.87 NPC1 (0.56) TRPV1ALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL9148530 0.82 TRPV1 (0.55) TRPV1ALDH1A1NPC1RAB9AL3MBTL1
SCHEMBL8658139 0.80 KMT2A (0.51) TRPV1ALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL27523120 0.79 CYP1A2 (0.60) TRPV1ALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL2233522 0.79 NPC1 (0.69) ALDH1A1KDM4ELMNASMN1; SMN2NPC1
SCHEMBL9149923 0.79 SMN1; SMN2 (0.56) ALDH1A1KDM4ELMNASMN1; SMN2NPC1
SCHEMBL9150331 0.78 NPC1 (0.54) ALDH1A1KDM4ELMNASMN1; SMN2NPC1
SCHEMBL8657991 0.78 ALDH1A1 (0.56) ALDH1A1KDM4ELMNASMN1; SMN2NPC1
SCHEMBL8955458 0.78 ALDH1A1 (0.55) ALDH1A1KDM4ELMNASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5476957-A Dye for heat sensitive recording MITSUI TOATSU CHEMICALS, INC. (JP) 1995-12-19 US disclosed
US-5346878-A Preservation stability of white portions and images MITSUI TOATSU CHEMICALS, INC. (JP) 1994-09-13 US disclosed
US-5306688-A Color-forming, electron donating compound and electron accepting compound; storage stability of uncolored portion MITSUI TOATSU CHEMICALS, INC. (JP) 1994-04-26 US disclosed