Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115672 | 0.88 | ALDH1A1 (0.63) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL9153663 | 0.79 | KDM4E (0.51) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL9147199 | 0.78 | TRPV1 (0.55) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL9151220 | 0.78 | NPC1 (0.56) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL2233522 | 0.78 | NPC1 (0.69) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL9151370 | 0.78 | SMN1; SMN2 (0.53) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL9149923 | 0.77 | SMN1; SMN2 (0.56) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL9153508 | 0.77 | SMN1; SMN2 (0.59) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL5696445 | 0.77 | ALDH1A1 (0.59) | KDM4EALDH1A1LMNASMN1; SMN2CTSV | |
| SCHEMBL8657491 | 0.76 | ALDH1A1 (0.56) | NPC1RAB9AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5476957-A | Dye for heat sensitive recording | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-12-19 | — | — | US | disclosed |
| US-5346878-A | Preservation stability of white portions and images | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-09-13 | — | — | US | disclosed |
| US-5306688-A | Color-forming, electron donating compound and electron accepting compound; storage stability of uncolored portion | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-04-26 | — | — | US | disclosed |