Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | BAD | Q92934 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308134 | 0.86 | DAO (0.57) | NPC1RAB9ASMN1; SMN2CES2CES1 | |
| SCHEMBL257372 | 0.86 | DAO (0.57) | NPC1RAB9ASMN1; SMN2CES2CES1 | |
| SCHEMBL27938589 | 0.82 | HPGD (0.46) | NPC1RAB9ASMN1; SMN2CES2CES1 | |
| SCHEMBL7814255 | 0.80 | KMT2A (0.73) | NPC1RAB9ASMN1; SMN2CES2CES1 | |
| SCHEMBL12551908 | 0.80 | CES2 (0.70) | NPC1RAB9ASMN1; SMN2CES2CES1 | |
| SCHEMBL1736339 | 0.80 | LTA4H (0.73) | NPC1RAB9ASMN1; SMN2CES2CES1 | |
| SCHEMBL8572071 | 0.80 | LTA4H (0.73) | NPC1RAB9ASMN1; SMN2CES2CES1 | |
| SCHEMBL238259 | 0.80 | LTA4H (0.73) | NPC1RAB9ASMN1; SMN2CES2CES1 | |
| SCHEMBL9725176 | 0.79 | MAPT (0.64) | RAB9ASMN1; SMN2CA1CA2HPGD | |
| SCHEMBL30632245 | 0.78 | LTA4H (0.70) | NPC1RAB9ASMN1; SMN2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420224-A | Films and fibers with benzoxazole groups | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1995-05-30 | — | — | US | disclosed |
| US-5354836-A | Polyarylene ether ketone, where at least one ring of the aromatic ketone unit is a thiophene ring | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1994-10-11 | — | — | US | disclosed |
| US-5266677-A | Aromatic polyamides | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1993-11-30 | — | — | US | disclosed |
| EP-0500493-A1 | Novel poly(arylene etherketones) | CIBA-GEIGY AG (CH) | 1992-08-26 | — | — | EP | disclosed |